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황색포도알균의 항생제 내성

 Antibiotic Resistance of Staphylococcus Aureus

KMID : 0869120060080010005
김윤경 ( Kim Yun-Kyung ) - 대구과학대학 간호과

정재심 ( Jeong Jae-Sim ) - 울산대학교 임상전문간호학
홍해숙 ( Hong Hae-Sook ) - 경북대학교 간호대학

Abstract

Staphyloccus aureus is one of the most important pathogens in clinical settings. It is also one of the leading causes of nosocomial infections and the dissemination of multiple drug-resistant strains, mainly methicillin resistant Staphyloccus aureus, and the recent emergence of a vancomycin resistant MRSA is the concern to hospital worldwide.
MRSA strains have acquired multiple resistance to a wide range of antibiotics, including aminoglycosides and macrolides. β-Lactam resistance of methicillin-resistnat Staphyococcus aureus is determined by the function of penicillin binding protein 2’(PBP2’) encoded by the methicillin resistance gene mec A. MRSA strains carry methicillin resistance gene mecA, encoded by a mobile genetic element designated staphylococcal cassette chromosome mec(SCCmec). MRSA clones are defined by the type of SCCmec element and the genotype of the methicilline-susceptible Staphyococcus aureus chromosome in which the SCCmec element is integrated.
KeyWords
황색포도알균, 항생제 내성
staphylococcus aureus, antibiotic resistance
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학술진흥재단(KCI) KoreaMed